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研究室

秋田大学大学院医学系研究科
医学専攻病態制御医学系
生体防御学講座

Department of Immunology

私たちは脂質とGPCRについて研究しています

Research Areas

  1. Establishment of (patho)physiological roles for lysophosphatidic acid (LPA)

  2. Characterization of intracellular signaling pathway of LPA receptors

  3. Identification of novel G-protein-coupled receptors for lipid mediators

News

▪️Sep 2026 Associate Professor Yasuda has been selected as a recipient of the 41st Basic Medical Research Grant from the Ichiro Kanehara Foundation for the Promotion of Medical Science and Medical Care.
▪️June 2026 Mr.Taira received the Best Student Presentation Award at The 68th Japanese Conference on the Biochemistry of Lipids
▪️April 2026 PhD student joined our lab.
▪️March 2026 Mr.Taira received the Research Achievement Award at the Research Doctor Camp
▪️Published a press release regarding the new paper
▪️Dec 2025 Lecturer Yasuda has been selected as a recipient of the Ono Medical Research Foundation's 2025 Research Grant.

Publication​s

*Yasuda, D., Sato, N., Yanagida, K., Hashidate-Yoshida, T., Shiiya, T., Shindou, H., Taira, A., Ebihara, T., Shimizu, T., Hirashima, M., Mizuno, S., Takahashi, S., and *Ishii, S. (2026) Lysophosphatidic acid-mediated NF-κB activation promotes FOXC2 expression essential for lymphatic valve development. J. Clin. Invest.,136:e193364.

​​Taketomi, Y., Higashi, T., Kano, K., Miki, Y., Mochizuki, C., Toyoshima, S., Okayama, Y., Nishito, Y., Nakae, S., Tanaka, S., Tokuoka, S.M., Oda, Y., Shichino, S., Ueha, S., Matsushima, K., Akahoshi, N., Ishii, S., Chun, J., Aoki, J., and Murakami, M. (2024) Lipid-orchestrated paracrine circuit coordinates mast cell maturation and anaphylaxis through functional interaction with fibroblasts. Immunity., 57:1828-1847. e11.

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